Matushita develops DNA technology to control disease

TOKYO – Matusushita Electrical Industrial Co. claims to have developed technology that can determine a person’s response to medication as well as their risk of developing diseases.

Matsushita, better known through its well-established brand, Panasonic, collaborated with researchers at Konan University for this project. The company claims the technology is the first of its kind in the world. The technology uses artificial DNA that is dissolved in a solution rather than being attached to an electrode.

The technology electronically identifies sequence variations in a specific DNA strand, called single nucleotide polymorphisms, or SNP’s. An SNP refers to one base pair and its position in the DNA sequence that is different from the other base pair. It is these differences in base pairs which are said to generate individual differences in each person’s reaction to drugs, development diseases and other health related factors.

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Diabetes Drugs Should Undergo More Testing, FDA Panel Recommends

Diabetes drugs must go through longer studies to make it certain that they are free from unexpected heart risks; this has been recommended by a government panel. It may cost pharmaceutical companies millions but it is protective for the patients to avoid unexpected heart risks.

On Wednesday, with a 14-2 voting, the advisers of the Food and Drug Administration recommended that all new diabetes drugs must have undergone longer studies to make it certain that they didn’t boost cardiovascular problems risks.

The diabetes experts, cardiologists and statisticians opined for less than a year after the FDA was badly criticized regarding managing the issue of GlaxoSmithKline’s commonly used pill. The drug was recommended in 1999 but FDA didn’t warn about possible heart risks till last November.

Many members of the panel suggested that drug companies should start safety tests before submitting any drug to the FDA, and they also complete the studies after the availability of the drugs in the market. The testing would cost tens of millions of dollars to the drug manufactures and will take a time of five to seven years to complete.

According to Dr. Eric Felner who is a pediatric specialist at Emroy University School of Medicine, “If such amount of time is spent for testing, it will be certainly preventing some drugs that may prove better than the already available drugs.”

It is not essential for FDA to follow the advice of the panel but it often does. Almost 24 million Americans are the victim of Type 2 diabetes that can cause kidney failure, blindness and heart disease.

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