Archive for June, 2008

Accidental Fungus Hoping Competitive Tumor Drug

200px-aspergillus_fumigatus.jpgWASHINGTON : A drug made of using nanotechnology and a fungus tarnished some laboratory experiments might be widely effective against a range of cancers, The U.S researchers said on Sunday.

The drug known Lodamin had been improved in one of the last experiments investigated by Dr. Judah Folkman, a cancer researcher who died in January. Folkman led the idea of angiogenesis therapy ravenous tumors by holding over them from rising blood supplies.

Lodamin is an angiogenesis inhibitor that Folkman’s team has been running just right for 20 years. Writing in the journal Nature Biotechnology, his colleagues said they developed a formula working as a pill with no side-effects.

Tests in mice showed it worked against a range of cancers including breast cancer, neuroblastoma, ovarian cancer, prostate cancer, brain tumors called as glioblastomas and uterine tumors.

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HIV sweeps back in MSM

hiv2.jpgAmong U.S. males ages 13 to 24, cases climbed up to 12 percent

According to U.S. health officials report, there is an alarming increase of HIV cases among men especially young one who have sex with men.
The term that has been used for these people by Public health experts is “men who have sex with men” or MSM as several among them neither homosexual nor even bisexual.

According to a report from Centers for Disease Control and Prevention, It has been noted that during 2001 to 2006, the largest HIV transmission group in the U.S was male-to-male sex group.

The greatest increase was of 12.4 percent among 13 to 24 years old males who had sex with other males and the increase was even more in ethnic minorities.

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Senate reaches a tentative deal on worldwide AIDS bill

aids-pic3.gifTo fight diseases like AIDS, malaria and tuberculosis worldwide, the senate has reached to a tentative agreement to authorize a federal program again.

The President’s Emergency Plan for AIDS Relief was suggested with $15 billion in funding at the time of its creation five years back. Now the extension of the plan suggested $50 billion more to control HIV and AIDS in many countries of the world. Due to concerns over increased spending, seven Republican senators led by Tom Coburn had stalled that plan.

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The first Lung cancer vaccine has been approved by the Cuban authorities.

19349.jpgCuban authorities have approved the first vaccine for use to increase the lives of patients with lung cancer and the vaccine is available in Cuban hospitals, told Cuban scientist on Tuesday.

The drug named Cima Vax EGF has shown good results to raise survival rates of four to five months and even longer in some patients on average basis, the scientists stated in a new conference at Cuba’s Center of Molecular Immunology.
Contrary to chemotherapy, Cima Vax EGF has fewer side effects because it contains modified proteins that target only the cancer cells.

The scientists told that there were other vaccines currently being tested in other parts of the world but CimaVax EGF was the first lung cancer approved vaccine anywhere in the world.
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Higher death rates have been noted in people with low levels of vitamin D

images.jpgThe findings of a new research suggest that low levels of vitamin D may increase death risk from heart disease and other causes. It provides critical evidence about the role of vitamin D for good sound health.

The study found that the patients who had the lowest levels of vitamin D in their blood had two times higher odds to die from any disease in the coming eight years of their lives than those whose levels of vitamin D were at the highest levels.

According to experts, these results mustn’t be seen as a reason to spend hours in the sun and start popping vitamin D pills. …Click here to read more

Specific form of beta-amyloid may cause Alzheimer’s, results of a new research suggest.

5.jpgA new clue to the cause of Alzheimer’s disease has been discovered by the researchers. A sticky protein known as beta-amyloid, clutter the brains of people that have memory-robbing form of dementia. But this is still a riddle whether this sticky protein is a side effect or a cause of the disease. Tangles of a protein known as tau are also involved in this procedure, some scientists considering it a cause.

Injecting rats with a specific kind of beta-amyloid, the researchers caused Alzheimer’s symptoms in them. The researchers noted that other kinds of beta-amyloid when injected to the rats, it didn’t cause illness in them. It shows that some people have beta-amyloid plaque in their brains but don’t have symptoms of the disease.

These findings were reported in online issue of the journal …Click here to read more

Although Big Breakfast Help Women in Weight Loss Yet Return To Obesity

heavy-bf.jpgThe scientists from Venezuela and the United States of America have found an amazing factor that big breakfast including carbohydrates and protein and then containing low carbohydrate and little calorie diet for the rest of the day tended to be more and more successful remedial measure in losing fats and keeping healthy and smart. This plan is being designed for the domestic and job holder women.

This study was presented at The Endocrine Society’s 90th Annual Meeting in San Francisco on Tuesday 17th June, by the guide writer Dr Daniela Jakubowicz of the Hospital de Clinicas, Caracas, Venezuela.

Jakubowicz, who conducted study along with the scientists of the United States from Virginia Commonwealth University in Richmond, elucidated that the most of the weight loss studies have shown us that a very lesser amount of carbohydrate diet is not a good method in reducing the high fats.

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Baja California Cleared of Salmonella Doubt, Yet the Suspicions

WASHINGTON: Baja California, the part of Mexico got clearance in the epidemic of “Salmonella-Tainted-Tomatoes”, but the U.S officials couldn’t find any of the consequences.

Meanwhile, the Food and Drug Administration (FDA) is trying its best to find out the major factors of the salmonella infection that led many American into illness. The restaurants and hotels are being investigated by the team of the U.S regime and FDA.

The officials of the FDA have found the solitary reason that there had been a large amount of tainted-tomatoes in the hotels and restaurants of the United States.

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Improvement in Dementia Symptoms via bright light

dementia.gifA optimal improvement in dementia symptoms has been linked with the use of bright light in daytime, for the improvement of their circadian rhythms, according to a study released on June 10, 2008 in JAMA. More over, the melatonin is also helpful in improving sleep.

Dementia is a costant decline in cognitive ability with the passage of time, and usually elderly patients suffer from this condition. These symptoms can have many contributing factors, according to the authors: “In elderly patients with dementia, cognitive decline is frequently increase by disturbances of mood, behavior, sleep, and activities of daily routine life, which enhance caregiver burden and the risk of institutionalization.”

Several biological processes in many organisms recur within 24 hours that is referred as a circadian rhythm. Although this rhythm is internal but it can be affected by various factors including the presence or absense of daylight. In humans, melatonin levels considered to be the yard stick in measuring the circadian cycle, and sometimes melatonin is used to maintain a regular rhythm. Abnormalities of imbalanced rhythms are quite familiar which include jet lag and Seasonal Affective Disorder (SAD.)

According to the authors, the circadian rhythm can also be

linked with the symptoms of dementia in the elderly stage: “The circadian timing system is extremely sensitive to environmental light and the melatonin hormone may not function properly in the absence of their synchronizing effects. In elderly patients with dementia, synchronization may be abolished if light exposure and melatonin production is reduced from certain level.” …Click here to read more

Enormous Impacts of High Cholesterol

High cholesterol emerged as one of the dangerous diseases in the world. Millions of people are involving in the disease of high cholesterol. Therefore it is estimated that every second American has caught up with symptoms of high cholesterol.

The lifestyles of the people have changed. People are used to binge eating that includes various kinds of foodstuffs, such as heavy cheese, butter, oily and spicy foodstuffs, enormous amounts of sweets and cookies, etc.

The patterns of keeping healthy and fit body have gone away. Now people don’t perform kinds of exercises, such as brisk walking, jogging, sprinting, swimming, yoga exercise, dance trainings, and weight lifting, etc.

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Shifting From Open To Robotic Prostatectomy

Institutional impact on number of pelvic lymph nodes retrieved during RALRP while using robotic and open prostatectomy.

Open pelvic lymph node surgery (PLND) remains the best choice in patients with transitional and high-risk prostate cancer undergoing radical retro-pubic prostatectomy (RRP). A group in Rhode Island has adopted robotic-assisted for radical prostatectomy. They wanted to conclude whether robot-assisted laparoscopic PLND yields equivalent numbers of lymph nodes in comparison with open PLND.

After the approval of IRB institute, the databases of open and robotic prostatectomy reviewed at this institution. Patients undergoing RALRP with robotic PLND over a period of one year and patients undergoing open radical prostatectomy with open PLND within the last 5 years were documented. The pathology reports of surgery were keenly examined again to decide the number of lymph nodes obtained from each surgery of PLND. Statistical analysis was performed using Student’s t-test.

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Istradfeylline may cut tremors related to Parkinson

According to a new study, Parkinson’s patients, who struggle against tics, spasm, tremors that usually occur when main medications is diminished, may be helped by a new drug.
Istradfeylline helps nerve and brain signals bypass and the spoiled dopamine system that be the cause of Parkinson.

In a trial 395 people with Parkinson who used levodopa (a well-known Parkinson’s drug) were found with 24% higher “off” than those who were using Istradfeylline. The “off” has been defined as a time when physical symptoms begins to appear after wearing off the drug levodopa.Similarly, in a group studied who took a placebo showed 10 % drop in “Off” time.

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